Imaging of endolymphatic and perilymphatic fluid at 3T after intratympanic administration of gadolinium-diethylene-triamine pentaacetic acid.
نویسندگان
چکیده
By optimizing the inversion time of a 3D inversion-recovery turbo spin-echo sequence at 3T, we obtained separate images of endolymphatic and perilymphatic space 24 hours after intratympanic administration of gadolinium contrast material. In patients with Ménière disease, endolymphatic hydrops were detected not only in the cochlea but also in the vestibule. Fusion of the 2 types of images visualized the entire fluid space of the labyrinth and the spatial relationship of the 2 spaces.
منابع مشابه
Intratympanic Contrast in the Evaluation of Menière Disease: Understanding the Limits.
BACKGROUND AND PURPOSE Studies describing endolymphatic hydrops in Menière disease after off-label intratympanic gadolinium-based contrast have been limited by long acquisition times. We aimed to demonstrate the feasibility of post-intratympanic imaging on a 3T MR imaging system within a clinically tolerable acquisition time and to address potential pitfalls in acquisition or interpretation. ...
متن کاملCoupling Gd-DTPA with a bispecific, recombinant protein anti-EGFR-iRGD complex improves tumor targeting in MRI
Recombinant anti‑epidermal growth factor receptor‑internalizing arginine‑glycine‑aspartic acid (anti‑EGFR single‑domain antibody fused with iRGD peptide) protein efficiently targets the EGFR extracellular domain and integrin αvβ/β5, and shows a high penetration into cells. Thus, this protein may improve penetration of conjugated drugs into the deep zone of gastric cancer multicellular 3D sphero...
متن کاملCASE REPORT Secondary Endolymphatic Hydrops Following Sudden Deafness Detected by MRI after Intratympanic Administration of Gadolinium
the hydrops by image analyses. A 64 years-old female who showed partial recovery of hearing disturbance two months after the onset of sudden deafness underwent inner ear MRI in combination with intratympanic injection of gadolinium. Two-dimensional fluid-attenuated inversion recovery (2D-FLAIR) sequences taken by 3 tesla MR unit showed endolymphatic hydrops in the cochlea. Electrocochleogram co...
متن کاملMagnetic Resonance Imaging of Intramedullary Epidermoid Cyst of Low Thoracic Spinal Cord: a case report MING-TSUNG WANG TAI-CHING WU JYH-CHING CHEN TSUNG-CHIA TSAI TAI-YOUENG CHEN WEN-SHENG TZENG JINN-MING CHANG
Intramedullary epidermoid cysts of the spinal cord are rare tumors. They are slow-growing tumors. We report a case of a 74-year-old patient presenting with thoracic spinal cord compression syndrome (T11-12). The magnetic resonance imaging (MRI) showed an intramedullary cystic mass. It demonstrated low signal intensity on T1and high signal intensity on T2-weighted images, with minimal peripheral...
متن کاملPenetration of the blood-brain barrier: enhancement of drug delivery and imaging by bacterial glycopeptides
The blood-brain barrier restricts the passage of many pharmacological agents into the brain parenchyma. Bacterial glycopeptides induce enhanced blood-brain barrier permeability when they are present in the subarachnoid space during meningitis. By presenting such glycopeptides intravenously, blood-brain barrier permeability in rabbits was enhanced in a reversible time- and dose-dependent manner ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 29 4 شماره
صفحات -
تاریخ انتشار 2008